[She's worried about him and how deeply this is hitting him. Whatever "this" is, but she'd be lying if she said there wasn't a flicker of nervousness at the way he's talking. Her initial thought is that of course she wouldn't feel that way. Of course she'd still want him whatever it is, but the thought that he's been hiding things, maybe lying to her without any idea that he was doing so is...unsettling. It's why she doesn't offer any upfront comfort to let him know it couldn't happen.
Action
She nods before giving a more audible answer.]
Of course.